BDBM50235626 CHEMBL4075197

SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1c1cn(C)c2ccccc12

InChI Key InChIKey=ZNFRUVZPVKADAA-VGSWGCGISA-N

Data  2 KI  2 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50235626   

TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235626(CHEMBL4075197)
Affinity DataKi:  10nMAssay Description:Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235626(CHEMBL4075197)
Affinity DataKi:  13nMAssay Description:Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235626(CHEMBL4075197)
Affinity DataKd:  150nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235626(CHEMBL4075197)
Affinity DataKd:  90nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235626(CHEMBL4075197)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of EED in human OCILY19 cells assessed as reduction in H3K27 trymethylation measured after 6 days by alphaLISA methodMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235626(CHEMBL4075197)
Affinity DataIC50:  4.10E+3nMAssay Description:In vitro test for inhibitory activity against human dipeptidyl peptidase IV.More data for this Ligand-Target Pair