BDBM50236003 CHEMBL4096234

SMILES N#Cc1c2CCN(Cc3ccccc3)Cc2c2nncn2c1NCc1ccco1

InChI Key InChIKey=QBTUKQKTXYTWPD-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50236003   

TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  4.03E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged EED (76 to 441 residues) (unknown origin) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL asses...More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  620nMAssay Description:Inhibition of recombinant N-terminal GST-tagged EED (76 to 441 residues) (unknown origin) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL incub...More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  4.03E+3nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  320nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction of global H3K27Me3 level by ELISAMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  4.03E+3nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  620nMAssay Description:Inhibition of biotinylated H3K27Me3 peptide (19 to 33 aa) binding to EED (1 to 441 residues) (unknown origin) expressed in Escherichia coli BL21-Codo...More data for this Ligand-Target Pair