BDBM50236826 CHEMBL4065841

SMILES N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CC(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=FDAGDZVCWKCEEX-NGYIUDBNSA-N

Data  3 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50236826   

TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50236826(CHEMBL4065841)
Affinity DataKi:  18nMAssay Description:Inhibition of recombinant human IRAP expressed in GnT1 deficient HEK293S cells using L-leucine 7-amido-4-methyl coumarin as substrate after 5 to 10 m...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50236826(CHEMBL4065841)
Affinity DataKi:  200nMAssay Description:Inhibition of recombinant human ERAP2 using L-arginyl-7-amido-4-methyl coumarin as substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50236826(CHEMBL4065841)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of binding of [3H]citalopram to (SERT) serotonin transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50236826(CHEMBL4065841)
Affinity DataIC50:  32nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50236826(CHEMBL4065841)
Affinity DataIC50:  3.69E+3nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50236826(CHEMBL4065841)
Affinity DataIC50:  740nMAssay Description:Inhibition of ERAP2 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed