BDBM50237357 CHEMBL4060030

SMILES Nc1nccc(n1)N(Cc1ccccc1)c1ccccc1-c1cccc(c1)-c1cnc(nc1)N1CCNCC1

InChI Key InChIKey=FRBABIFCTILEGV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50237357   

TargetTumor necrosis factor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50237357(CHEMBL4060030)
Affinity DataIC50:  1.20E+3nMAssay Description:Binding affinity to human TNF-alpha soluble domain assessed as decrease in complex formation with human TNFR1 extracellular domain preincubated for 1...More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50237357(CHEMBL4060030)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity to human TNF-alpha soluble domain assessed as decrease in complex formation with human TNFR2 extracellular domain preincubated for 1...More data for this Ligand-Target Pair