BDBM50239059 CHEMBL4059503
SMILES CN(C)c1nc2ccc(cc2c(Cl)c1-c1ccccc1)C(O)(c1cncn1C)c1ccncc1
InChI Key InChIKey=SEJAMGYPDDPTHR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50239059
Affinity DataIC50: 7.5nMAssay Description:Inverse agonist activity at GAL4 DBD-fused human RORgammat expressed in HEK293T cells assessed as inhibition of transcriptional activity after 24 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inverse agonist activity at GAL4 DBD-fused human RORgammat expressed in HEK293T cells assessed as inhibition of transcriptional activity after 24 hrs...More data for this Ligand-Target Pair
Affinity DataKd: 290nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKd: 290nMAssay Description:Displacement of 1,8-ANS from recombinant human RORgammat LBD expressed in Escherichia coli BL21 (DE3) cells assessed as inhibition of co-activator SR...More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inverse agonist activity at GAL4 DBD-fused human RORgammat expressed in HEK293T cells assessed as inhibition of transcriptional activity after 24 hrs...More data for this Ligand-Target Pair
Affinity DataKd: 290nMAssay Description:Displacement of 1,8-ANS from recombinant human RORgammat LBD expressed in Escherichia coli BL21 (DE3) cells assessed as inhibition of co-activator SR...More data for this Ligand-Target Pair