BDBM50239069 CHEMBL4079036
SMILES COc1nc2ccc(cc2c(Cl)c1-c1ccc(cc1)S(C)(=O)=O)C(O)(c1cncn1C)c1ccc(nc1)C(F)(F)F
InChI Key InChIKey=GBSZBTDJEFDZLG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50239069
Affinity DataKd: 37nMAssay Description:Displacement of 1,8-ANS from recombinant human RORgammat LBD expressed in Escherichia coli BL21 (DE3) cells assessed as inhibition of co-activator SR...More data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Transactivation of RORgammat in human Th17 cells assessed as increase in IL17A productionMore data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Transactivation of GAL4 DBD-fused human RORgammat expressed in HEK293T cells assessed as stimulation of transcriptional activity after 24 hrs by Dual...More data for this Ligand-Target Pair