BDBM50239946 CHEMBL4084368

SMILES Cc1cc(CN[C@H](CO)C(O)=O)c(OCc2cccc(c2)C#N)cc1OCc1cccc(c1C)-c1ccc2OCCOc2c1

InChI Key InChIKey=UWNXGZKSIKQKAH-SSEXGKCCSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50239946   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50239946(CHEMBL4084368)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity to His-tagged PD-L1 (unknown origin) assessed as reduction in PD-L1/PD1-Ig interaction preincubated with PD-L1 for 15 mins followed ...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50239946(CHEMBL4084368)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity at human C-terminal His-tagged PD-L1 (18 to 239 residues)/human C-terminal IgG epitope-tagged PD1 (25 to 167 residues) expressed ...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50239946(CHEMBL4084368)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of PD-1 (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM50239946(CHEMBL4084368)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human PD-1/PD-L1 interactionMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50239946(CHEMBL4084368)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human PD-1/PDL1 by HTRF assayMore data for this Ligand-Target Pair