BDBM50240569 CHEMBL4067893

SMILES [H][C@]12COC(=O)N1C(=O)[C@@]([H])(NC2)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(cc(c1)C(=O)N[C@H](C)c1ccccc1)N(C)S(C)(=O)=O

InChI Key InChIKey=WEUUCSVIFAYVCD-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240569   

TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50240569(CHEMBL4067893)
Affinity DataKi:  23nMAssay Description:Inhibition of recombinant human BACE1 (Ala8P to Ala326 residues) expressed in Escherichia coli BL21(DE3) using Arg-Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2019
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50240569(CHEMBL4067893)
Affinity DataEC50:  80nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2019
Entry Details Article
PubMed