BDBM50240873 CHEMBL4068596
SMILES Nc1nc(Cl)c2cnn(Cc3cc4OCOc4cc3Br)c2n1
InChI Key InChIKey=BIABSXPPEYWVER-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50240873
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Affinity DataIC50: 698nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 448nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant N-terminal Grp94 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Affinity DataIC50: 431nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant N-terminal HSP90alpha (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair