BDBM50240875 CHEMBL4080323

SMILES COc1c(C)cnc(Cn2ncc3c(Cl)nc(N)nc23)c1C

InChI Key InChIKey=IKGRZHVFOMUXCQ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240875   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandPNGBDBM50240875(CHEMBL4080323)
Affinity DataIC50:  97nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandPNGBDBM50240875(CHEMBL4080323)
Affinity DataIC50:  138nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair