BDBM50243467 1-[1-(4-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride::CHEMBL459644

SMILES OC1(CCCCC1)C(CN1CCNCC1)c1ccc(Cl)cc1

InChI Key InChIKey=KHWNQEDSMGUKSX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243467   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243467(1-[1-(4-Chlorophenyl)-2-piperazin-1-ylethyl]cycloh...)
Affinity DataKi:  717nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243467(1-[1-(4-Chlorophenyl)-2-piperazin-1-ylethyl]cycloh...)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of 5HT uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed