BDBM50244031 3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL452812

SMILES COc1ccc(cc1)C1=C(C(=O)NC1)c1c[nH]c2ccccc12

InChI Key InChIKey=XIOUIJRUBUIKSA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50244031   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244031(3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244031(3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human recombinant Aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244031(3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant ARK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244031(3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244031(3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human recombinant CDK4/cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244031(3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244031(3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of human recombinant FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244031(3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed