BDBM50244211 6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-4-yl)piperazin-1-yl)methyl)quinoxaline-2,3(1H,4H)-dione::6-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-yl]-piperazin-1-ylmethyl}-1,4-dihydro-quinoxaline-2,3-dione::CHEMBL459215
SMILES CC(C)(C)c1ccc(cc1)-c1nc2c(cccc2[nH]1)N1CCN(Cc2ccc3[nH]c(=O)c(=O)[nH]c3c2)CC1
InChI Key InChIKey=IFRHRAPSJRMCTF-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50244211
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at recombinant GnRH receptor in CO2 asphyxiated rat primary pituitary cells assessed as reduction in (D-Trp6)LHRH-induced LH rele...More data for this Ligand-Target Pair