BDBM50244350 CHEMBL4091374
SMILES OC(=O)CCCc1cc2cc(Cl)ccc2n1S(=O)(=O)c1ccc2ncsc2c1
InChI Key InChIKey=OQDQIFQRNZIEEJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50244350
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inventiva
Curated by ChEMBL
Inventiva
Curated by ChEMBL
Affinity DataEC50: 866nMAssay Description:Transactivation of human GAL4-fused PPARdelta LBD expressed in African green monkey COS7 cells co-expressing 5Gal4 pGL3 TK Luc after overnight incuba...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 210nMAssay Description:Agonist activity at human PPARgammaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.14E+3nMAssay Description:Displacement of N-terminal biotin-labeled SMRT-ID1 (2339 to 2363 residues) from recombinant GST-tagged PPARgamma (unknown origin) expressed in Escher...More data for this Ligand-Target Pair
Affinity DataEC50: 4.10E+3nMAssay Description:Displacement of N-terminal biotin-labeled NCOR-ID1 (2253 to 2277 residues) from recombinant GST-tagged PPARgamma (unknown origin) expressed in Escher...More data for this Ligand-Target Pair
Affinity DataEC50: 727nMAssay Description:Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled LCOR (39 to ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.48E+3nMAssay Description:Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled NCoA3 (607 t...More data for this Ligand-Target Pair
Affinity DataEC50: 1.92E+3nMAssay Description:Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled NCoA3 (671 t...More data for this Ligand-Target Pair
Affinity DataEC50: 3.21E+3nMAssay Description:Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled PGC1alpha (1...More data for this Ligand-Target Pair
Affinity DataEC50: 4.11E+3nMAssay Description:Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled PNRC1 (302 t...More data for this Ligand-Target Pair
Affinity DataEC50: 3.27E+3nMAssay Description:Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled RIP140 (922 ...More data for this Ligand-Target Pair
Affinity DataEC50: 366nMAssay Description:Transactivation of mouse GAL4-fused PPARalpha LBD expressed in African green monkey COS7 cells co-expressing 5Gal4 pGL3 TK Luc after overnight incuba...More data for this Ligand-Target Pair
Affinity DataEC50: 1.56E+3nMAssay Description:Transactivation of mouse GAL4-fused PPARdelta LBD expressed in African green monkey COS7 cells co-expressing 5Gal4 pGL3 TK Luc after overnight incuba...More data for this Ligand-Target Pair
Affinity DataEC50: 202nMAssay Description:Transactivation of mouse GAL4-fused PPARgamma LBD expressed in African green monkey COS7 cells co-expressing 5Gal4 pGL3 TK Luc after overnight incuba...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inventiva
Curated by ChEMBL
Inventiva
Curated by ChEMBL
Affinity DataEC50: 1.54E+3nMAssay Description:Transactivation of human GAL4-fused PPARalpha LBD expressed in African green monkey COS7 cells co-expressing 5Gal4 pGL3 TK Luc after overnight incuba...More data for this Ligand-Target Pair
Affinity DataEC50: 3.41E+3nMAssay Description:Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled SRC1 (619 to...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inventiva
Curated by ChEMBL
Inventiva
Curated by ChEMBL
Affinity DataEC50: 3.06E+3nMAssay Description:Agonist activity at PPARalpha (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inventiva
Curated by ChEMBL
Inventiva
Curated by ChEMBL
Affinity DataEC50: 2.96E+3nMAssay Description:Agonist activity at PPARdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 559nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inventiva
Curated by ChEMBL
Inventiva
Curated by ChEMBL
Affinity DataEC50: 1.50E+3nMAssay Description:Agonist activity at human PPARalphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inventiva
Curated by ChEMBL
Inventiva
Curated by ChEMBL
Affinity DataEC50: 870nMAssay Description:Agonist activity at human PPARdeltaMore data for this Ligand-Target Pair
Affinity DataEC50: 206nMAssay Description:Transactivation of human GAL4-fused PPARgamma LBD expressed in African green monkey COS7 cells co-expressing 5Gal4 pGL3 TK Luc after overnight incuba...More data for this Ligand-Target Pair