BDBM50248250 Thiocolchicine Glycoside::Thiocolchicoside

SMILES COc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc2CCC(NC(C)=O)c3cc(=O)c(SC)ccc3-c2c1OC

InChI Key InChIKey=LEQAKWQJCITZNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248250   

TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50248250(Thiocolchicine Glycoside | Thiocolchicoside)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed