BDBM50251893 (2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pentanedioic acid::(2S,4R)-4-(3-Benzylamino-3-oxopropyl)glutamic acid::CHEMBL518313

SMILES N[C@@H](C[C@@H](CCC(=O)NCc1ccccc1)C(O)=O)C(O)=O

InChI Key InChIKey=HMSFZCZUJKRFNW-NEPJUHHUSA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50251893   

TargetGlutamate receptor ionotropic, kainate 1(RAT)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)
Affinity DataKi:  138nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)
Affinity DataKi:  2.14E+4nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)
Affinity DataKi:  4.10E+5nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)
Affinity DataKi:  1.00E+6nMAssay Description:Inhibition of [3H]D-Asp uptake at EAAT1 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of glutamate-induced depolarization in human human EAAT2 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of glutamate-induced depolarization in human human EAAT3 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of glutamate-induced depolarization in human EAAT1 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed