BDBM50254986 5-bromo-1H-indazol-3-amine::CHEMBL465091::EN300-223999

SMILES Nc1n[nH]c2ccc(Br)cc12

InChI Key InChIKey=OMPYFDJVSAMSMA-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254986   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Sgx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50254986(5-bromo-1H-indazol-3-amine | CHEMBL465091 | EN300-...)
Affinity DataIC50:  4.09E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50254986(5-bromo-1H-indazol-3-amine | CHEMBL465091 | EN300-...)
Affinity DataIC50:  2.32E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In DepthDetails PubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50254986(5-bromo-1H-indazol-3-amine | CHEMBL465091 | EN300-...)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed