BDBM50259900 CHEMBL4101947

SMILES COc1cccc(CC2CCCNC2)c1

InChI Key InChIKey=GQKSLDMVANTJRX-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259900   

TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50259900(CHEMBL4101947)
Affinity DataKd:  3.20E+4nMAssay Description:Inhibition of EED in human G401 cells assessed as reduction in H3K27 methylation measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50259900(CHEMBL4101947)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of human PRC2-EED (76 to 441 residues) expressed in Escherichia coli BL21 (DE3) using histone H3[21 to 44, K27MeO] as substrate and SAM as...More data for this Ligand-Target Pair