BDBM50260148 CHEMBL4070885

SMILES Fc1ccc(cc1C(=O)NCc1ccccn1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1

InChI Key InChIKey=DXYYFJOVZVSYFY-RXVVDRJESA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260148   

TargetG protein-coupled receptor kinase 5(Bos taurus)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50260148(CHEMBL4070885)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50260148(CHEMBL4070885)
Affinity DataIC50:  610nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
TargetRhodopsin kinase GRK1(Bos taurus)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50260148(CHEMBL4070885)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity of compound towards dopamine transporter determined using [3H]WIN-35 428 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed