BDBM50265751 4-Amino-7-(methylamino)-3-[6-(4-methylpiperazinyl)benzimidazol-2-yl]hydroquinolin-2-one::CHEMBL449593

SMILES CNc1ccc2c(N)c(-c3nc4ccc(cc4[nH]3)N3CCN(C)CC3)c(=O)[nH]c2c1

InChI Key InChIKey=CAAQXWCBWGARSL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265751   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265751(4-Amino-7-(methylamino)-3-[6-(4-methylpiperazinyl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265751(4-Amino-7-(methylamino)-3-[6-(4-methylpiperazinyl)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265751(4-Amino-7-(methylamino)-3-[6-(4-methylpiperazinyl)...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed