BDBM50267296 CHEMBL4104658

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn2CCCc3cccc1c23

InChI Key InChIKey=CLXOEYRLLVMPJB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267296   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Nanjing Normal University

Curated by ChEMBL
LigandPNGBDBM50267296(CHEMBL4104658)
Affinity DataIC50:  8.46E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by lonWorks Quattro analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50267296(CHEMBL4104658)
Affinity DataIC50:  405nMAssay Description:Inhibition of EGR-induced EGFR phosphorylation in human A549 cells pretreated for 2 hrs followed by EGF stimulation by immune assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50267296(CHEMBL4104658)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant cytoplasmic GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed