BDBM50267521 3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxybenzofuran-3-yl)pyrrole-2,5-dione::CHEMBL523435

SMILES COc1cccc2c(coc12)C1=C(C(=O)NC1=O)c1cn(C)c2cc(I)c(F)cc12

InChI Key InChIKey=JBKILIGSDAQHSL-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50267521   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IKKalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50:  247nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed