BDBM50268023 CHEMBL4078038
SMILES Fc1ccc(NS(=O)(=O)c2cccc(Cl)c2)c(F)c1C#Cc1cnc2[nH]nc(OC3CCCC3)c2c1
InChI Key InChIKey=NAWXZADRFFCXNH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50268023
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University of Macau
Curated by ChEMBL
University of Macau
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild type GST-tagged recombinant human full-length B-RAF expressed in baculovirus expression system using Ser/Thr3 as substrate after 1...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
University of Macau
Curated by ChEMBL
University of Macau
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full-length ZAK expressed in baculovirus infected Sf9 insect cells using MBP as substrate after...More data for this Ligand-Target Pair