BDBM50273636 4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzamide::CHEMBL511337

SMILES NC(=O)c1ccc(Nc2cc(n[nH]2)-c2ccc(F)cc2)cc1

InChI Key InChIKey=QKAONCSNINNEGU-UHFFFAOYSA-N

Data  9 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50273636   

TargetSerine/threonine-protein kinase 17A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273636(4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzami...)
Affinity DataKd:  96nMAssay Description:Binding affinity to human DRAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273636(4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzami...)
Affinity DataKd:  1.23E+3nMAssay Description:Binding affinity to human MNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase MARK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273636(4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzami...)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to human MARK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek7(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273636(4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzami...)
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to human NEK7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273636(4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzami...)
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to human LIMK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273636(4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzami...)
Affinity DataKd:  111nMAssay Description:Binding affinity to human KITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273636(4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzami...)
Affinity DataKd:  42nMAssay Description:Binding affinity to human PDGFRBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273636(4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzami...)
Affinity DataKd:  30nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273636(4-(5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)benzami...)
Affinity DataKd:  367nMAssay Description:Binding affinity to human GAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed