BDBM50276373 CHEMBL4125713

SMILES [H][C@@]12CO[C@@]([H])(O1)C(=O)C(F)=C2

InChI Key InChIKey=AULOPSOAILWXGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276373   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
The Noguchi Institute

Curated by ChEMBL
LigandPNGBDBM50276373(CHEMBL4125713)
Affinity DataIC50: 800nMAssay Description:Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
The Noguchi Institute

Curated by ChEMBL
LigandPNGBDBM50276373(CHEMBL4125713)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed