BDBM50277407 CHEMBL473288::N-(4-bromophenyl)-4-(pyridin-4-ylmethylamino)isothiazole-3-carboxamide
SMILES Brc1ccc(NC(=O)c2nscc2NCc2ccncc2)cc1
InChI Key InChIKey=KFOLYIMICUBNES-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50277407
Affinity DataKi: 70nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC90 concentration by ATP based competition assayMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC50 concentration by ATP based competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of VEGFR1 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISAMore data for this Ligand-Target Pair