BDBM50277595 CHEMBL445281::N-((2S,3S)-4-(3-(2H-tetrazol-5-yl)phenylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-4-bromo-6-((S)-4-phenyloxazolidine-3-carbonyl)picolinamide

SMILES O[C@@H]([C@H](Cc1ccccc1)NC(=O)c1cc(Br)cc(n1)C(=O)N1COC[C@@H]1c1ccccc1)C(=O)Nc1cccc(c1)-c1nnn[nH]1

InChI Key InChIKey=VJRDPWORFMXZOD-OYFGVDPJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277595   

TargetBeta-secretase 1(Homo sapiens (Human))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50277595(CHEMBL445281 | N-((2S,3S)-4-(3-(2H-tetrazol-5-yl)p...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50277595(CHEMBL445281 | N-((2S,3S)-4-(3-(2H-tetrazol-5-yl)p...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed