BDBM50279270 (Z)-3-[(4-Dimethylaminomethyl-phenylamino)-phenyl-methylene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylic Acid Methyl Ester::CHEMBL498105

SMILES COC(=O)c1ccc2C(C(=Nc3ccc(CN(C)C)cc3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=LSJAPABXQBDHRE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50279270   

TargetPlatelet-derived growth factor receptor alpha(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279270((Z)-3-[(4-Dimethylaminomethyl-phenylamino)-phenyl-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279270((Z)-3-[(4-Dimethylaminomethyl-phenylamino)-phenyl-...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279270((Z)-3-[(4-Dimethylaminomethyl-phenylamino)-phenyl-...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279270((Z)-3-[(4-Dimethylaminomethyl-phenylamino)-phenyl-...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279270((Z)-3-[(4-Dimethylaminomethyl-phenylamino)-phenyl-...)
Affinity DataIC50: 173nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed