BDBM50285447 CHEMBL53397::{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsulfanyl]-pentyl}-butyl-(5-tert-butyl-benzooxazol-2-yl)-amine

SMILES CCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2cc(ccc2o1)C(C)(C)C

InChI Key InChIKey=ROYQJKVQYGXCIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285447   

TargetSterol O-acyltransferase 1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285447(CHEMBL53397 | {5-[4,5-Bis-(4-methoxy-phenyl)-1H-im...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285447(CHEMBL53397 | {5-[4,5-Bis-(4-methoxy-phenyl)-1H-im...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assayMore data for this Ligand-Target Pair
In DepthDetails Article