BDBM50295558 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide::CHEMBL1191::SULFAMETHIZOLE

SMILES Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

InChI Key InChIKey=VACCAVUAMIDAGB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295558   

TargetCytochrome P450 3A4(Human)
Jadavpur University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295558BDBM50295558(4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenes...)
Affinity DataIC50: 8.36E+5nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50295558BDBM50295558(4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenes...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed