BDBM50296987 (R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[2,3-b]indolizin-10-yl)acetic acid::CHEMBL557117

SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ncccc3n2C1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=NROVVWMGTIZNGL-CQSZACIVSA-N

Data  3 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50296987   

TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataKi: >1.30E+3nMAssay Description:Displacement of radioligand from prostanoid DP receptor expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataKi: >7.00E+3nMAssay Description:Displacement of radioligand from prostanoid TP receptor expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataKi:  7.19E+3nMAssay Description:Displacement of radioligand from human CRTH2 expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]SQ-29548 from thromboxane receptor in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50:  4.17E+4nMAssay Description:Displacement of [3H]PGD2 from prostaglandin D1 receptor in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50:  2.49E+4nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50:  5.10E+4nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptor in presence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296987((R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]iloprost from human prostacyclin receptor expressed in human 293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed