BDBM50299382 4-((3-acetylphenyl)(1-benzylpiperidin-4-yl)amino)-N,N-diethylbenzamide::CHEMBL576740

SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(c1)C(C)=O

InChI Key InChIKey=JSLRBQOORJVJEV-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299382   

TargetDelta-type opioid receptor(Human)
Astrazeneca R & D Montr£Al

Curated by ChEMBL
LigandPNGBDBM50299382(4-((3-acetylphenyl)(1-benzylpiperidin-4-yl)amino)-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R & D Montr£Al

Curated by ChEMBL
LigandPNGBDBM50299382(4-((3-acetylphenyl)(1-benzylpiperidin-4-yl)amino)-...)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R & D Montr£Al

Curated by ChEMBL
LigandPNGBDBM50299382(4-((3-acetylphenyl)(1-benzylpiperidin-4-yl)amino)-...)
Affinity DataKi:  1.54E+3nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R & D Montr£Al

Curated by ChEMBL
LigandPNGBDBM50299382(4-((3-acetylphenyl)(1-benzylpiperidin-4-yl)amino)-...)
Affinity DataKi:  4.54E+3nMAssay Description:Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed