BDBM50308000 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazol-2-yl)benzofuran-6-sulfonamide::CHEMBL598832

SMILES CCc1oc2cc(ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1)S(=O)(=O)Nc1nccs1

InChI Key InChIKey=KTISQHZPQUEIPS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50308000   

TargetSerine/threonine-protein phosphatase 2A activator(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50:  6.67E+4nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50308000(3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(thiazo...)
Affinity DataIC50:  8.00E+3nMAssay Description:Allosteric inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed