BDBM50308170 (3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfonyl)-1H-indazol-5-yl]pyrrolidin-3-amine::CHEMBL599466

SMILES CC(C)n1nc(c2cc(ccc12)N1CC[C@@H](N)C1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=QNVKMRYWPVDPHU-GOSISDBHSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308170   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308170((3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...)
Affinity DataKi:  13.7nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308170((3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...)
Affinity DataKi:  191nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50308170((3R)-1-[1-(1-Methylethyl)-3-(naphthalen-1-ylsulfon...)
Affinity DataIC50:  157nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed