BDBM50308792 (3-(3-(1-benzylpiperidin-4-yl)-7-morpholino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl)methanol::CHEMBL592064

SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2nnn(C3CCN(Cc4ccccc4)CC3)c2n1

InChI Key InChIKey=JYBBCFSRQXKJMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308792   

LigandChemical structure of BindingDB Monomer ID 50308792BDBM50308792((3-(3-(1-benzylpiperidin-4-yl)-7-morpholino-3H-[1,...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308792BDBM50308792((3-(3-(1-benzylpiperidin-4-yl)-7-morpholino-3H-[1,...)
Affinity DataIC50: 250nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50308792BDBM50308792((3-(3-(1-benzylpiperidin-4-yl)-7-morpholino-3H-[1,...)
Affinity DataIC50: 435nMAssay Description:Inhibition of human PI3Kgamma by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed