BDBM50311474 2-(1'-(4-isopropylcyclohexyl)-2-oxospiro[benzo[d][1,3]oxazine-4,4'-piperidine]-1(2H)-yl)-N-methylacetamide::CHEMBL1076208

SMILES CNC(=O)CN1C(=O)OC2(CCN(CC2)C2CCC(CC2)C(C)C)c2ccccc12

InChI Key InChIKey=XSGGRILSKJJOSZ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311474   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50311474(2-(1'-(4-isopropylcyclohexyl)-2-oxospiro[benzo[d][...)
Affinity DataKi:  106nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50311474(2-(1'-(4-isopropylcyclohexyl)-2-oxospiro[benzo[d][...)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50311474(2-(1'-(4-isopropylcyclohexyl)-2-oxospiro[benzo[d][...)
Affinity DataIC50: 448nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed