BDBM50312652 1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethyl-6-cyano-3-[2,2-difluoro-2-phenylethylamino]pyrazinone::CHEMBL1084908
SMILES [#7]\[#6](-[#7])=[#7]\[#8]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-n1c(cnc(-[#7]-[#6]C(F)(F)c2ccccc2)c1=O)C#N
InChI Key InChIKey=NIKUFUKVJGORCK-UHFFFAOYSA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50312652
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 6.50E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of cathepsin GMore data for this Ligand-Target Pair
TargetChymase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair