BDBM50313125 8-(1-(pyrrolidin-3-yl)-1H-indol-3-ylsulfonyl)quinoline::CHEMBL1080729

SMILES O=S(=O)(c1cn(C2CCNC2)c2ccccc12)c1cccc2cccnc12

InChI Key InChIKey=DYBDWJMYDAUKFY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313125   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313125(8-(1-(pyrrolidin-3-yl)-1H-indol-3-ylsulfonyl)quino...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313125(8-(1-(pyrrolidin-3-yl)-1H-indol-3-ylsulfonyl)quino...)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed