BDBM50314617 (2S,6R)-4-((3,5-dimethylisoxazol-4-yl)methoxy)-2,6-difluorobenzyl 2,6-dimethylpiperazine-1-carboxylate::CHEMBL1091452

SMILES C[C@H]1CNC[C@@H](C)N1C(=O)OCc1c(F)cc(OCc2c(C)noc2C)cc1F

InChI Key InChIKey=IIHSKABITVJBTL-TXEJJXNPSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314617   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314617((2S,6R)-4-((3,5-dimethylisoxazol-4-yl)methoxy)-2,6...)
Affinity DataKi:  43nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314617((2S,6R)-4-((3,5-dimethylisoxazol-4-yl)methoxy)-2,6...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314617((2S,6R)-4-((3,5-dimethylisoxazol-4-yl)methoxy)-2,6...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at Homo sapiens (human) 5-HT2C receptor assessed as 5-HT-induced calcium mobilization by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article