BDBM50315685 ((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-propylpiperidin-1-yl)methanone::CHEMBL1090161

SMILES CCC[C@]1(O)[C@@H](C)CN(C[C@H]1C)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C

InChI Key InChIKey=BQZXWVJPEGSSMW-TVLLSFCTSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315685   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315685(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataKi:  844nMAssay Description:Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315685(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataEC50:  126nMAssay Description:Agonist activity at human recombinant MC4 receptor expressed in CHO cells by cAMP responsive beta lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315685(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataEC50:  3.61E+3nMAssay Description:Agonist activity at human recombinant MC1 receptor expressed in HEK293 cells assessed as cAMP accumulation by enzyme fragment complementation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315685(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataEC50: >2.47E+4nMAssay Description:Agonist activity at human recombinant MC3 receptor expressed in CHO cells assessed as cAMP accumulation by enzyme fragment complementation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed