BDBM50315739 3-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-7H-pyrrolo-[2,3-d]pyrimidin-2-yl}phenol::CHEMBL1089443

SMILES CN(C)CCn1ccc2c(nc(nc12)-c1cccc(O)c1)N1CCOCC1

InChI Key InChIKey=ZQHXGKGYHLTMOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315739   

LigandChemical structure of BindingDB Monomer ID 50315739BDBM50315739(3-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-7H-...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315739BDBM50315739(3-{7-[2-(Dimethylamino)ethyl]-4-morpholin-4-yl-7H-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed