BDBM50316269 4-(4-Morpholin-4-yl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)aniline::CHEMBL1097263

SMILES Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(-c3ccccc3)c2n1

InChI Key InChIKey=CBRULMYFULTTGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316269   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316269BDBM50316269(4-(4-Morpholin-4-yl-1-phenyl-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316269BDBM50316269(4-(4-Morpholin-4-yl-1-phenyl-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50: 290nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed