BDBM50317777 CHEMBL1099223::dimethyl 2,4,6-trimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

SMILES COC(=O)C1C(C)=NC(C)=C(C(=O)OC)C1(C)c1ccccc1

InChI Key InChIKey=ZGXJMBYNJXMZKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317777   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Rabbit)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50317777(dimethyl 2,4,6-trimethyl-4-phenyl-1,4-dihydropyrid...)
Affinity DataIC50: 1.47E+3nMAssay Description:Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50317777(dimethyl 2,4,6-trimethyl-4-phenyl-1,4-dihydropyrid...)
Affinity DataIC50: 2.31E+3nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed