BDBM50324344 CHEMBL1215360::Cyclohexyl-(6-piperazin-1-yl-4-trifluoromethyl[2,4']bipyridinyl-2'-yl)amine

SMILES FC(F)(F)c1cc(nc(c1)-c1ccnc(NC2CCCCC2)c1)N1CCNCC1

InChI Key InChIKey=CNLCKMDXRXVYMV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324344   

TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324344(CHEMBL1215360 | Cyclohexyl-(6-piperazin-1-yl-4-tri...)
Affinity DataEC50:  342nMAssay Description:Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324344(CHEMBL1215360 | Cyclohexyl-(6-piperazin-1-yl-4-tri...)
Affinity DataIC50:  101nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324344(CHEMBL1215360 | Cyclohexyl-(6-piperazin-1-yl-4-tri...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed