BDBM50328507 2-Amino-7-benzyl-4-(4-methoxyphenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile::CHEMBL1258990

SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(Cc1ccccc1)C2

InChI Key InChIKey=XMFMGIZJBWFAOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328507   

TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328507(2-Amino-7-benzyl-4-(4-methoxyphenyl)-5-oxo-5,6,7,8...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as inhibition of 3[H]-D-Aspartate uptake after 6 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328507(2-Amino-7-benzyl-4-(4-methoxyphenyl)-5-oxo-5,6,7,8...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed