BDBM50330788 CHEMBL1277500::N1-Methyl-N2-phenyl-N2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-ethane-1,2-diamine

SMILES CNCCN(c1ccccc1)c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=LBBBRPSDINTRFT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50330788   

TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]-N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed