BDBM50331031 (Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5-(2-morpholin-4-yl-ethyl)-5,6,7,8-tetrahydro-1H-pyrrolo[3,2-c]azepin-4-one::CHEMBL1277071
SMILES Cc1c(\C=C2/C(=O)Nc3ccc(F)cc23)[nH]c2CCCN(CCN3CCOCC3)C(=O)c12
InChI Key InChIKey=GRDPLDYSIKQSRC-JXAWBTAJSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50331031
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Shanghai Hengrui Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair