BDBM50333978 CHEMBL1644471::exo-(1R,5S)-3-phenoxy-8-azabicyclo[3.2.1]octane

SMILES C1C[C@@H]2C[C@H](C[C@H]1N2)Oc1ccccc1

InChI Key InChIKey=HQWOOKZKFBMBCD-PTEHBNRSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333978   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333978(CHEMBL1644471 | exo-(1R,5S)-3-phenoxy-8-azabicyclo...)
Affinity DataIC50:  5.66E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333978(CHEMBL1644471 | exo-(1R,5S)-3-phenoxy-8-azabicyclo...)
Affinity DataIC50:  54nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333978(CHEMBL1644471 | exo-(1R,5S)-3-phenoxy-8-azabicyclo...)
Affinity DataIC50:  737nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed