BDBM50334146 (S)-N-(1-(4-(2H-tetrazol-5-yl)phenyl)ethyl)-1-(4-(trifluoromethyl)benzyl)indoline-7-carboxamide::CHEMBL1645152

SMILES C[C@H](NC(=O)c1cccc2CCN(Cc3ccc(cc3)C(F)(F)F)c12)c1ccc(cc1)-c1nnn[nH]1

InChI Key InChIKey=DIYWIQWQEJPXAR-INIZCTEOSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334146   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50334146((S)-N-(1-(4-(2H-tetrazol-5-yl)phenyl)ethyl)-1-(4-(...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50334146((S)-N-(1-(4-(2H-tetrazol-5-yl)phenyl)ethyl)-1-(4-(...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed