BDBM50334360 4-(3-(4-acetylphenyl)ureido)benzenesulfonamide::4-{([(4'-Acetylphenyl)amino]carbonyl)amino}benzenesulfonamide::CA IX inhibitor, (C)2::CHEMBL1643295

SMILES CC(=O)c1ccc(NC(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1

InChI Key InChIKey=QDFITLNSSXUDGW-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50334360   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334360(4-(3-(4-acetylphenyl)ureido)benzenesulfonamide | 4...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 12 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Bc Cancer Agency

LigandPNGBDBM50334360(4-(3-(4-acetylphenyl)ureido)benzenesulfonamide | 4...)
Affinity DataKi:  5.40nMAssay Description:The inhibition constants (Ki) of FEC to four human CA isoenzymes I, II, IX and XII were determined by CA catalyzed CO2 hydration assays following pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Bc Cancer Agency

LigandPNGBDBM50334360(4-(3-(4-acetylphenyl)ureido)benzenesulfonamide | 4...)
Affinity DataKi:  5.40nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 9 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM50334360(4-(3-(4-acetylphenyl)ureido)benzenesulfonamide | 4...)
Affinity DataKi:  75nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv3273 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334360(4-(3-(4-acetylphenyl)ureido)benzenesulfonamide | 4...)
Affinity DataKi:  388nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM50334360(4-(3-(4-acetylphenyl)ureido)benzenesulfonamide | 4...)
Affinity DataKi:  470nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv1284 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334360(4-(3-(4-acetylphenyl)ureido)benzenesulfonamide | 4...)
Affinity DataKi:  1.06E+3nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334360(4-(3-(4-acetylphenyl)ureido)benzenesulfonamide | 4...)
Affinity DataKi:  1.06E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed